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产品详情
  • 产品名称:异氟烷

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简单介绍:
产品名称:异氟烷;异氟烷是动物吸入式麻醉剂,是动物麻醉机主要耗材
详情介绍:

异氟烷简介

【化学名】2--2-二氟甲氧基-111-三氟乙烷

【英文名】Isoflurane

【成份】本品主要成分异氟烷

【化学式】CF3CHCIOCHF2  

【规格】100ml   

【保质期】3年           

异氟烷是动物吸入式麻醉剂,是动物麻醉机主要耗材 。
友诚生物科技有限公司推荐的异氟烷动物吸入式麻醉方式,属气体吸入式麻醉,动物麻醉诱导和复苏都非常较快。异氟烷比恩氟烷更少经过生物转化,几乎完全由肺清 除,对肝药酶系统的诱导很小,因此对药代试验和毒理试验干扰较小。麻醉时无交感神经系统兴奋现象,可使心脏对肾上腺素的作用稍有增敏,有一定的肌松作用。带给动物的并发症少,死亡率低;实验重复性好;对动物的生理指标影响更小;适合于大鼠、小鼠、兔子、狗、猴子等各种实验动物;是国际上*为流行的麻醉方法。

异氟烷麻醉与传统麻醉的对比




1.传统的麻醉的方法
  • 乙醚麻醉 不适用于麻醉诱导;遇氧易燃、易爆,使用不方便,它的使用已日趋减少且逐渐被淘汰。
  • 注射麻醉 具有严重的呼吸及心血管抑制作用,有短的呼吸暂停作用;止痛作用较差;不适用于肝、肾疾 病的动物;复苏比较困难,需要严格控制剂量,容易造成意外,死亡率比较高。

2.吸入式气体(异氟烷)麻醉
  • 适用于短期麻醉,利于更改麻醉方案,麻醉速度快,苏醒快,麻醉时间可控。
  • 可通过麻醉气体浓度精 确调控麻醉深度,使用方便、安全。
  • 吸入和消除都在动物肺部,极少被动物吸收,不会产生肝肾毒性
  • 适用范围更广,尤其针对深入和长时间的麻醉实验,气体麻醉更为适用。

综上所述,异氟烷气体麻醉并发症少,死亡率低;实验重复性好;不会影响动物的生理指标;适合于各种动物;国际惯用麻醉方法,成果易于得到国际承认。



异氟烷的使用方法

异氟烷属于无色透明的液体,易挥发,是一种全身***,它通过动物呼吸吸入肺内进入血管,经血液循环到达大脑,抑制中 枢神经系统,可达到止痛和无意识的双重功效。

使用时,会储放于专门的密闭挥发罐(常安装于小动物吸入式麻醉气体麻醉机上)里,在外部气源(氧气或者空气)经管路流经异氟烷液体表面时,由于异氟烷的易挥发性,由液体变为气体,与氧气或者空气混合流出挥发罐,再连接诱导盒或者动物麻醉面罩,供动物诱导麻醉和持续麻醉。其诱导或维持麻醉浓度可通过挥发罐上的浓度控制盘随时进行0-5%的浓度准确调节,氧气或者空气的流量根据动物的种类和大小用流量计进行调节。

此外,异氟烷与氧气或空气的混合气体还可以供呼吸机使用,起到麻醉和辅助呼吸的双重作用。不管是配合麻醉机还是呼吸机,亦或者是脑立体定位仪,都可以参考我公司的动物麻醉解决方案。

仅 限于动物实验使用

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